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2022

L Travier, R Singh, D Sáenz Fernández, A Deczkowska

Microbial and immune factors regulate brain maintenance and aging

Current Opinion in Neurobiology. 2022.

M Cohen, A Giladi, O Barboy, P Hamon, B Li, M Zada, A Gurevich-Shapiro, C Gabriel Beccaria, E David, B Maier, M Buckup, I Kamer, A Deczkowska, J Le Berichel, Jair Bar, M Iannacone, A Tanay, M Merad, I Amit

The interaction of CD4+ helper T cells with dendritic cells shapes the tumor microenvironment and immune checkpoint blockade response

Nature Cancer. 2022.

A Dominguez-Belloso, S Schmutz, S Novault, L Travier, A Deczkowska 

Isolation and Characterization of the Immune Cells from Micro-dissected Mouse Choroid Plexuses

JoVE. 2022.

 

2021

Deczkowska A, David E, Ramadori P, Pfister D, Safran M, Li B, Giladi A, ... , Weiner A, Ben-Ari Z, Heikenwälder M, Elinav E & Amit I

XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis

Nature Medicine. 2021.

Pfister D, Gonzalo Núñez N, Pinyol R, Govaere O, Pinter M, Szydlowska M, Gupta R, Qiu M, Deczkowska A, Weiner A, Müller F, ...

NASH limits anti-tumour surveillance in immunotherapy-treated HCC

Nature. 2021.

 

2020

Cohen M, Giladi A, Raposo C, Zada M, Li B, Ruckh J, Deczkowska A, Mohar B, Shechter R, Lichtenstein RG, Amit I, Schwartz M

Meningeal lymphoid structures are activated under acute and chronic spinal cord pathologies 

Life Science Alliance. 2020.

Deczkowska A, Weiner A, Amit I.

The Physiology, Pathology, and Potential Therapeutic Applications of the TREM2 Signaling Pathway. 

Cell. 2020. 

 

Bost P, Giladi A, Liu Y, Bendjelal Y, Xu G, David E, Blecher-Gonen R, Cohen M, Medaglia C, Li H, Deczkowska A, Zhang S, Schwikowski B, Zhang Z, Amit I.

Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients.

Cell. 2020. 

2019

Jaitin DA, Adlung L, Thaiss CA, Weiner A, Li B, Descamps H, Lundgren P, Bleriot C, Liu Z, Deczkowska A, Keren-Shaul H, David E, Zmora N, Eldar SM, Lubezky N, Shibolet O, Hill DA, Lazar MA, Colonna M, Ginhoux F, Shapiro H, Elinav E, Amit I.

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner.

Cell. 2019.

Kertser A, Baruch K, Deczkowska A, Weiner A, Croese T, Kenigsbuch M, Cooper I, Tsoory M, Ben-Hamo S, Amit I, Schwartz M.

Corticosteroid signaling at the brain-immune interface impedes coping with severe psychological stress.

Sci Adv. 2019. 

2018

Deczkowska A, Schwartz M.

Targeting neuro-immune communication in neurodegeneration: Challenges and opportunities.

J Exp Med. 2018.

Deczkowska A, Keren-Shaul H, Weiner A, Colonna M, Schwartz M, Amit I.

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration.
Cell. 2018.

Deczkowska A, Amit I, Schwartz M.

Microglial immune checkpoint mechanisms.

Nat Neurosci. 2018.

2017

Deczkowska A, Matcovitch-Natan O, Tsitsou-Kampeli A, Ben-Hamo S, Dvir- Szternfeld R, Spinrad A, Singer O, David E, Winter DR, Smith LK, Kertser A, Baruch K, Rosenzweig N, Terem A, Prinz M, Villeda S, Citri A, Amit I, Schwartz M.

Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner.

Nat Commun. 2017. 

Deczkowska A.

Let's talk about language barriers.

Science. 2017.​

Deczkowska A, Schwartz M.

NIX-ing mitochondria: from development to pathology.

EMBO J. 2017.

2016

Schwartz M, Deczkowska A.

Neurological Disease as a Failure of Brain-Immune Crosstalk: The Multiple Faces of Neuroinflammation.

Trends Immunol. 2016.

Matcovitch-Natan O, Winter DR, Giladi A, Vargas Aguilar S, Spinrad A, Sarrazin S, Ben-Yehuda H, David E, Zelada González F, Perrin P, Keren-Shaul H, Gury M, Lara-Astaiso D, Thaiss CA, Cohen M, Bahar Halpern K, Baruch K, Deczkowska A, Lorenzo-Vivas E, Itzkovitz S, Elinav E, Sieweke MH, Schwartz M, Amit I.

Microglia development follows a stepwise program to regulate brain homeostasis.

Science. 2016.

Deczkowska A, Schwartz M.

Making Ends Meet: Myeloid Cells Catalyze Blood Vessel Repair in the Brain.

Immunity. 2016. 

Deczkowska A, Baruch K, Schwartz M.

Type I/II Interferon Balance in the Regulation of Brain Physiology and Pathology.

Trends Immunol. 2016.

Baruch K, Deczkowska A, Rosenzweig N, Tsitsou-Kampeli A, Sharif AM, Matcovitch-Natan O, Kertser A, David E, Amit I, Schwartz M.

PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease.

Nat Med. 2016. 

2015

Baruch K, Rosenzweig N, Kertser A, Deczkowska A, Sharif AM, Spinrad A, Tsitsou-Kampeli A, Sarel A, Cahalon L, Schwartz M.

Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology.
Nat Commun. 2015. 

Wen J, Doerner J, Weidenheim K, Xia Y, Stock A, Michaelson JS, Baruch K, Deczkowska A, Gulinello M, Schwartz M, Burkly LC, Putterman C.

TNF-like weak inducer of apoptosis promotes blood brain barrier disruption and increases neuronal cell death in MRL/lpr mice.

J Autoimmun. 2015.

2014

Baruch K, Deczkowska A, David E,Castellano JM, Miller O, Kertser A, Berkutzki T, Barnett-Itzhaki Z, Bezalel D,Wyss-Coray T, Amit I,Schwartz M.
Aging-induced type I interferon response at the choroid plexus negatively affects brain function.

Science. 2014.

 

2013

Shifrut E, Baruch K, Gal H, Ndifon W, Deczkowska A, Schwartz M, Friedman N.
CD4(+) T Cell-Receptor Repertoire Diversity is Compromised in the Spleen but Not in the Bone Marrow of Aged Mice Due to Private and Sporadic Clonal Expansions.

Front Immunol. 2013. 

Baruch K, Ron-Harel N, Gal H, Deczkowska A, Shifrut E, Ndifon W, Mirlas-Neisberg N, Cardon M, Vaknin I, Cahalon L, Berkutzki T, Mattson MP, Gomez-Pinilla F, Friedman N, Schwartz M.

CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging.

PNAS. 2013.  

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